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Ofloxacin - General information

Ofloxacin is an antibiotic, fluroquinolone. It provides a fast and broad antibacterial action. The drug prevents the division of bacteria, causes the changes in DNA chains of microorganisms destroying them on cellicololis level. As a result of the destabilization of the molecular DNA of bacteria they quickly die and Ofloxacin prevents the occasional infection. Due to this, the patient feel the protection. If you often experience the symptoms of the common infectious inflammatory diseases, it is time to think about the purchase of Ofloxacin and stop the frequent relapses of the infections in your body.  

Each antibiotic has its own peculiarity and Ofloxacin is not an exception. This medicine is effective as to microorganisms resistant to most antibiotics (penicillin, etc). Ofloxacin is active as to microorganisms producing b-lactamase and quickly-growing atypical bacteria which destroy other antibacterial components and do not give to destroy bacterial completely.

Directions for the use Ofloxacin

Ofloxacin is used for the treatment of the infections caused by gram-positive and gram-negative microorganisms:

  • airway tracts (pneumonia, attack of bronchitis)
  • ENT (sinusitis, pharyngitis, otitis media, laryngitis, tracheitis)
  • Skin and soft tissue
  • Bones and Joints
  • gastrointestinal tract,
  • pelvic organs, kidney and urinary tract
  • Acute infection of genitals: gonorrhea, prostatitis
  • chlamydial infections

Ofloxacin may be used for the treatment of tuberculosis in complex therapy. In this case, you may buy Ofloxacin and use it as an additional product in the lower dosage.

Ofloxacin: Dosage details

Ofloxacin provides a prolonged therapeutic effect, therefore the daily dosages up to 400 mg may be used once. Usually, patients with infections of the middle level of the severity are prescribed 200-400 mg per day, once, preferably in the morning, during breakfast.

In case of no results in 3-4 days after the beginning of the treatment, the dose may be increased up to 800 mg per day (1 tablet of Ofloxacin 400 mg 2 times a day, in the morning and evening).

After the disappearance of the infection signs the treatment lasts for 2-3 days in order to completely remove bacteria. On the average, the length of the therapy is 3-5 days in case of the light infections, and 10-12 days – severe ones.

The longer antibacterial therapy is not needed. In case of no results of the treatment, it is necessary to have the examination and find out the type of the infection. Perhaps, the use of Ofloxacin is ineffective in your clinical case and another antibiotic is required.

Ofloxacin: Side effects

Unlike other representative of fluroquinolones Ofloxacin has fewer side effects. It is conditioned by its chemical structure which has been developed in order to reduce the reactions in most patient. But using this antibiotic some side effects may happen such as painful sensations in the stomach, headache, tremor, spasms, numbness of extremities, anxiety, taste disorder, olfaction disorder, tachycardia, and lowering of the blood pressure.

In order to avoid the adverse reactions it is needed to follow the instruction for the use without increasing the daily dosage and take the tablets during meals.

Interaction with other medical products

  • it is contraindicated to take Ofloxacin with heparine
  • antacids reduce the uptake of Ofloxacin
  • furosemide, cimetidine, and metothrexate increase the concentration of Ofloxacin in the blood plasma as a result of which the dose of the antibiotic must be adjusted.
  • Prescribing it with non-steroid anti-inflammatory drugs the risk of neurotoxic effects is increased.


The symptoms of the overdose are: confusion, retardation, disorientation, sleepiness, and vomiting.

If you took too high dose and has these symptoms, it is needed to immediately have the symptomatic therapy, stomach lavage, and seek the qualified help of the physician.

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Brand names include: Floxin / Floxstat / Ocuflox / Novecin / Oflo / Oflox / Taravid /

Active ingredient: nitrofurantoin

Class: Urinary anti-infectives

Formulation Type :  Pills 100, 200,300, 400 mg

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